Fakitale yogulitsira mtengo wabwino kwambiri Sodium triacetoxyborohydride ufa CAS 56553-60-7

Njira yotumizira yotetezeka CAS 56553-60-7 ufa Sodium triacetoxyborohydride
Dzina la malonda: Sodium triacetoxyborohydride
CAS: 56553-60-7
Mapangidwe a maselo: C6H10BNaO6
Maonekedwe: ufa woyera
Zomwe zili: 95.0% ~ 105.0% (titration)
Ntchito: Pakuchepetsa amination reaction ya ketone ndi aldehyde, reductive amination kapena lactamization ya carbonyl compound ndi amine, and reductive amination of aryl aldehyde.
Mphamvu: 5 ~ 10mt / mwezi

Sodium triacetoxyborohydride (STAB) CAS 56553-60-7 yomwe imadziwikanso kuti sodium triacetoxyhydroborate, yomwe nthawi zambiri imafupikitsidwa STAB, ndi mankhwala omwe ali ndi formula Na(CH3COO)3BH.Monga ma borohydrides ena, amagwiritsidwa ntchito ngati chochepetsera mu kaphatikizidwe ka organic.Mchere wopanda mtundu uwu umakonzedwa ndi protonolysis ya sodium borohydride yokhala ndi acetic acid: NaBH4 + 3 HO2CCH3 → NaBH(O2CCH3)3 + 3 H2.

Chifukwa cha steric ndi zamagetsi zamagulu a acetoxy, sodium triacetoxyborohydride ndi yochepetsera pang'ono kuposa sodium borohydride kapena sodium cyanoborohydride.Kuphatikiza apo, NaBH(OAc)3 imapewa zinthu zapoizoni zomwe zimapangidwa ndi sodium cyanoborohydride.Sodium triacetoxyborohydride ndiyoyenera makamaka pakuchepetsa ma aldehydes ndi ma ketoni.

Komabe, mosiyana ndi sodium cyanoborohydride, triacetoxyborohydride imakhala yosamva madzi, ndipo madzi sangagwiritsidwe ntchito ngati zosungunulira ndi reagent iyi, komanso sizigwirizana ndi methanol.Imagwira pang'onopang'ono ndi ethanol ndi isopropanol ndipo ingagwiritsidwe ntchito ndi izi.NaBH(OAc)3 itha kugwiritsidwanso ntchito pochepetsa kuchepetsa ma amine achiwiri okhala ndi aldehyde-bisulfite adducts.